Posted By: impposter
Re: Apparently, you don’t remember it very well, IMP.
I remember that willy doesn't know how to read and then makes stuff up to try-and-fail to prove his points. Like most MAGAs, he reads a headline and or listens to a tiktok or just repeats Trump propaganda like a trained parrot.
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Where's the rest of the abstract?
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Abstract
Ivermectin ***proposes*** many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective against many microorganisms including some viruses. In this comprehensive systematic review, antiviral effects of ivermectin are summarized including ***in vitro*** and ***in vivo*** studies over the past 50 years. Several studies reported antiviral effects of ivermectin on RNA viruses such as Zika, dengue, yellow fever, West Nile, Hendra, Newcastle, Venezuelan equine encephalitis, chikungunya, Semliki Forest, Sindbis, Avian influenza A, Porcine Reproductive and Respiratory Syndrome, Human immunodeficiency virus type 1, and severe acute respiratory syndrome coronavirus 2. Furthermore, there are some studies showing antiviral effects of ivermectin against DNA viruses such as Equine herpes type 1, BK polyomavirus, pseudorabies, porcine circovirus 2, and bovine herpesvirus 1. Ivermectin plays a role in several biological mechanisms, therefore it ***could*** [or could ***NOT***] serve as a ***potential*** candidate in the treatment of a wide range of viruses including COVID-19 as well as other types of positive-sense single-stranded RNA viruses. **In vivo studies of *****animal models***** ** revealed a broad range of antiviral effects of ivermectin, *****however, clinical trials are necessary to appraise the potential efficacy of ivermectin in clinical setting.*****
... It may be concluded that ivermectin could be effective in the early stages of infection [with flavivirus] and ***may*** be a recommended drug for the **prevention** or **treatment** [**or not useful at all**] of early stages of [flavivirus] viral infection, rather than advanced forms. *******Of course, confirmation of this statement requires further human studies and clinical trials.*******
... The researchers concluded that ivermectin ***could be*** [might be, might NOT be; did not prove it to be clinically] effective in treating HEV infection by inhibiting the transmission of the virus by IMP α1/β1. ...
... "In this systematic review, we showed antiviral effects of ivermectin on a broad range of RNA and DNA viruses by reviewing all related evidences since 1970. This study presents the ****possibility**** that ivermectin could be a useful antiviral agent in several viruses including those with positive-sense single-stranded RNA, in similar fashion. Since significant *****effectiveness of ivermectin is seen in the **early stages of infection** in experimental studies,***** it is proposed that ivermectin administration may be effective in the early stages or prevention. ********Of course, confirmation of this statement requires human studies and clinical trials.********
As noted, *****the activity of ivermectin in cell culture has not reproduced in mouse infection models against many of the viruses and has not been clinically proven either,***** in spite of ivermectin being available globally. This is likely related to the pharmacokinetics and therapeutic safety window for ivermectin.
And this is the evidence that willy is relying upon to prove his position that ivermectin is ready to roll and wipe out Covid?????
Posted By: willywonka4u
Re: Apparently, you don’t remember it very well, IMP.
lol.
The rest of the abstract is right there in the link... it is this the reason you write out 50 page posts?