Alas, it is so, but then I was faced with a variety of regional labels with just one or two cities. Also, market characteristics played a role as well.
If I wanted to do this somewhat accurately, we'd have:
New England: Boston
Northeast: New York, New Jersey, Philadelphia
The Appalachians: Washington DC (in the foothills), Virginia, Carolinas, Atlanta
Great Lakes: Chicago, Wisconsin, Michigan, Pittsburgh, Indiana, Ohio
Southeast: Miami, Orlando/Tampa, North Florida
South: New Orleans, Dallas, San Antonio, Austin, Houston
Mid-South: Memphis, Nashville, Louisville
Mid-West: St. Louis, Kansas City
Rockies: Albuquerque, Colorado
South Desert: Arizona
Mid-Desert: Utah, Las Vegas
Northwest: Seattle, Portland
Northern California: San Francisco, Reno/Tahoe
Southern California: LA, San Diego