Downtown is best. Mission Valley is cheaper but touristy.

The Omni, The W,,  Happy Travels & welcome
to our beautiful City come July!

If you want to catch a Padre game while your here then the Omni. The W is cool too. Nice big tubs to enjoy with someone!

I concur Mr. Stern5565,  
Hehe, We know where the best big tub is...

Stay downtown.  Avoid Mission Valley.

parking is much better than downtown

Depends on the hotel.  Downtown hotels do offer parking, often times for a fee.  I've been to a few where I had to find street parking, which is sometimes metered parking.

Carmel Valley/Del Mar has easy hotel access.

Even if u stay a downtown hotel Kat, you will normally pay a parking fee each night. Also some hotels on Harbor Island, and Mission Bay are like that.
I hobby often, but never see a girl who incalls downtown due to parking.

I have no issue with paying for parking, but its the potential paper trail it leaves if it's a credit card only lot.
IMO a good hostess understands the situation at her incall and gives her clients a heads up on what to expect or a good place to go.

I've seen a number of ladies downtown and I don't have an issue with paying for parking.  

I'll bring the Mr. Bubble!

Unless the goal is to be off the beaten track, avoid staying in Carmel Valley. It is not near the beach, east of the I-5 in fact, and is in no way central unless one lives or works there. Downtown meets all the criteria, close to the harbor and beaches, great restaurants and bars, accessible.

Carmel Valley is 5mins from the beach in Del Mar or Torrey Pines