So I just got a response from the Escort saying that she is open on friday or next week. Do I tell her I am a 21 yr old "virgin"(new) now or after we set up an appointment?

You probably want to bring it up at some point prior to the date, though. I think the experience will be enhanced by a great provider if she has the knowledge that she is playing with a first-timer.

Good luck.
K

is to let her know you are in your 20's so she doesn't freak out seeing a young guy at her door or once you open your hotel room door.

Honestly i don't think most would mind how old you are as long as your calling them, lol
For me, after you've been verified and we were to set up an appt. and we've spoken on the phone a few times which usually happens with the gentlemen i see, you could mention it then. Not that the "date" would be any different, but it would be handled differently so it would be memorable for you.
Jay