If you are doing something illegal and the police have cause to enter or you allow them to enter.

get turned in by neighbors & busted...  in their own homes...   I do know one with a legit home based business which covers her low volume traffic.

Not only can you get busted in your own home, but you can also get cited for running a house of prostitution.

Best to get a hotel room. If you use your own home, guys can easily figure out your real identity. It just takes one flake to ruin your life.