To invoke RICO, one must be part of a criminal enterprise.  An independent would not qualify under this.

Perhaps an escort agency would, especially if it was big time, but I have not yet heard of such a thing happening.

RICO takes a lot of investigative work and is used for the big fish.  No LE would invoke it for a simple case of prostituion.

(still not a lawyer)

and attorneys tend to use the words as shorthand for seizure enabling statutes.  Chances are that you will not have to contend with the Fed RICO Act on a local prostitution bust absent extenuating circumstances such as human trafficking or being part of a larger criminal enterprise.  Those circumstances will draw the attention of the Feds, who will invoke the RICO penalties.

Local jurisdictions, however, have their own seizure enabling statutes that you could face.  If you operate out of your home, which is inadvisable for a number of reasons, you should meet with a local attorney to fully explore the issues.  Your state may very well have seizure laws that allow your house to be seized for this kind of crime, particularly if drugs are found on you, the client, or in your house.  There are plenty of examples when cars of single transaction drug buyers are seized, and the money found during a prostitution bust is typically seized as well.

Go see a lawyer, or bring back your attorney client and set up a true barter for some detailed legal advice.

(still a lawyer)

Maybe I watch too much TV, but one of the more disturbing aspects of RICO is that it deals with property, and property has no rights!!!  LE, local or federal, can stop you if they think you have done something wrong.  If they believe your car was result of illegal activity, they can seize it, and it is up to you to prove that it was obtained legally.  This technicality is an incentive for LE to vigorously enforce the law, and there are more than a few LE officers, (particularly in Florida),  now driving the cars, and boats, of people that were never convicted of anything!!!

There's both a federal and a Florida RICO law. Half of the states have state RICO laws, which for the most part mirror the federal RICO law.

Florida's prostitution laws:
http://tinyurl.com/ynkmsp

Florida's RICO law:
http://tinyurl.com/2eggkj

Notice that in section 895.02(1)(a)(25), prostitution is specifically listed as a crime that can constitute racketeering activity. It's unlawful to use the proceeds from racketeering activity to buy real property. All real property derived from such proceeds may be subject to civil forfeiture to the state. The forfeiture of your property does not depend upon conviction of a crime and can occur as soon an arrest.

It doesn't matter where you were arrested. All that matters is that the proceeds can be traced to a property interest. Separate bank accounts and not commingling funds helps to avoid tracing.

As for the federal RICO law, well, property can be forfeited under that too. Violations of the Mann Act and the Travel Act would constitute racketeering activity under the federal RICO statute. You can do a search of the board to find out about those two laws and if they apply.

By the way, for people who insist that RICO has to be some degree of a business enterprise, 18 USC § 1961(4) and Fla. Stat. § 895.02 both say enterprise can include individuals. There have been RICO convictions of individuals operating by themselves. For example, a guy making copies of copyrighted porn and selling them has been convicted under RICO.