90% of hotels and casinos are open.
99% of shows are dark.
Restaurants are open at reduced capacity.  
Most bars are open, also at reduced capacity.  
Some strip clubs are open, but with many rules.  
Golf and TopGolf are open.
Pools are open. I think some still require masks when not in the water, but that may have changed as restrictions are being loosened.

I'm not crazy regular, but I'll throw in what I've seen.

Pretty close to dead on Monday-(Wednesday?). Last time I was in town, the food court at Caesar's was closed, for instance. Pushing you hard towards the nicer restaurants, which I don't mind, but that might matter to some. As far as strip clubs, Sapphires was open 7 days, but Rhino is only open Thursday-Saturday. Other clubs might not be open at all, or open 7 days a week, or only open 3 days a week.

There are some dance (not stripper) clubs that have announced they're opening in March/April. I'd look into which clubs you're interested in and check the social media of each.

Some hotels, like Wynn, aren't open Monday-Wednesday, last I heard.

Seriously, the vibe is very different. Not trying to be an a-hole, here, but the people in town are not the people who visited in the past. It's amateur hour in Vegas right now. Lots of really cheap people, and not a lot of people who know how to tip well, etc.

I mean, it's worth going to because nowhere else is any better right now, except maybe Florida/Miami (?). Everywhere I've been, it's pretty much the same. Vegas is better than those places, if you're comparing 2021 in City X vs 2021 in Vegas, but it's nothing like 2019 Vegas, you know?