I called today (10/25) several time (4) to set-up an appointment and was unable to contact anyone.  I called at different hours to no avail.  It just rang and then the answering machine picked up.

Has this happened to anyone else?  Any ideas?  Has anyone heard anything?

Sometimes they post next week's schedule before opening Saturday.  It's possible they did not open yesterday, but you couldn't tell from the online schedule.

Yep, happened to me a couple of times. They have two numbers 212 586-8896 and 212 977 1376. Keep on tryin' as its a busy place. I also heard Domino will be back by April 04.

I was wondering because I did call them several times on Saturday, including around 4 PM.

If you called at 4:00PM and the phones were busy...you would get the answering machine. They were open....you should have just tried again.