I've read a number of very positive posts about Trimix injections on this forum and decided to try it. I'm a healthy, fit 72 year old with no underlying health issues, allergies, or medications other than ED pills. I underwent successful prostate radiation 8 years ago with no immediate side affects, but over time I've had to up my Viagra/Cialis dosage to the highest recommended level. Recently, even that has not always been as effective as I'd like.

After talking to my Urologist at a nationally respected health care system, we had a session where he instructed me as I administered my first shot. Most websites recommend an initial trial dose of 5-20 units/mcgs, with 20 being the most commonly mentioned dose. I went with 20 at the recommendation of my Urologist. The good news is that it worked really well. Within 30 minutes, I was as hard as I've EVER been. Leaving the clinic in that condition was a little embarrassing, but soon I was home. Being alone, I went ahead and masturbated to see how I would last afterwards, and eventually the bad news became evident. Nothing changed. At two hours I was still hard as a rock. I tried the home remedies of Sudafed and cold pack. Still no change! Given that I had received a supposedly conservative dose, and Priapism (the hard on doesn't go away) is a side effect with harmful consequences if left untreated, I called my Urologist and eventually returned to his office. He sent me to urgent care in the same building. Long story short, I was there for over 2 hours with a fairly extensive procedure including blood draws and more injections of meds (all in my cock) to counteract the Trimix. My now slightly painful wood finally started to soften about 4 1/2 hours after the fist shot.

Because I had taken the recommended initial dose, my Urologist thinks it was a reaction to one of the Trimix compounds. I wonder if I would have been ok if I started with an even more conservative does (5 - 10 units), but after what I went through, I don't dare try again. Bottom line, Trimix seems to be usually safe and more commonly prescribed  than I thought, but if you are at all risk averse, you might consider starting with very conservative dose. You can always up it later in conjunction with your Urologist recommendations.