I predict that Tom Izzo will once again lead his Michigan State Spartans to the Final Four.

As for slightly under the radar, Oregon, Indiana, Xavier, Purdue, Arizona could make a good run.  

Lastly, it would not surprise me if Utah makes it to the Elite Eight.

I just hope a 16 seed knocks off a 1. Can't wait to see the brackets tomorrow....best time of year!!!!  
Long shot, Miami...watch out for dem canes and Saint Mary.  
Shit I need to make a run to Vegas...

The seeding is really strange this year.

Can't understand how Michigan State won their conference tournament and has a higher ranking than Virginia, and gets a #2 seed, while Virginia lost their conference tournament and gets a #1 seed. Not sure what the selection committee was smoking, but it must have been some really good stuff.