1.Global Warming / Climate Change  
2. Civil War  
3. Poles Reversing  
4. Asteroid  
5. Artificial Intelligence  
6. Health Science advances giving Humans the ability to live 220 Years, longer if you have bribe $  
7.Nano technology, Bioengineering with devious intentions or Advanced Plague technology.  
8.Nuclear war  
9. Alien Invasion from another Galaxy.  
10. Alien Invasion from  Earth Born Radical Religion  
11.Pollution  
12.Lack of Potable Fresh water  
13.Massive Volcano Eruption  
14.Black Hole  
15. President Trump  
16. President Chelsea  
17. Driverless cars.  Don't laugh, when the poles reverse you will crash and burn.  
18. Crusades... See # 10 & # 2  
19.World War  
20. Massive Food Shortages  
21Poisoned Oceans  
22.Obesity
23.Rogue Interstellar Energy Wave  
24. Our Sun Runs out of Light
25. Proxima Centauri and Rigil Kentaurus collide causing # 14 and light year dominoes.
26. Ocean Life choked to death by carelessly discarded plastics.
27. Electrical Plants shut down due to Electromagnetic Pulse weapons, leading to Road Warrior 7
28. Fake News
29. ?    
   
   I believe # 11 Pollution, in synch with # 12  Lack of potable fresh water is the most dangerous to our livelihood  in the near future..... long before 2233