Ever since the dawn of man, he (or dawn of humans and he/she, if you want to be PC) has tried to alter consciousness for various reasons. It could be pharmacology, to treat an acute condition; recreational, because a few glasses of wine makes the conversation flow; or systemic, because you have problems or conditions consistently prevalent in your life that cause an emptiness/longing/need for something to cover up that emptiness.
A lot of the "old age" problems of cancer and ED didn't exist in the old days because the vast majority of people died before they reached the stage where physical age caused them problems. Correct me if I'm wrong, but at the time of Christ I think life expectancy wad 35 or so.
I think "maladaptive coping styles" are simply ways of dealing with things that people repeat. Even if the results are not what they wish, it's all they know how to do, so they repeat them and get the same results. The old Einstein conundrum. In these cases, people need to be shown that there are alternative methods of reacting to circumstances that could bring better results. Sometimes the drugs, either recreational or under the care of a guru or doctor, help with that. Other times you just need to talk to others (which could include a counselor) to find a different path.
Overmedicated? Yes. Americans want the pill to fix everything. They don't want to eat less. They want to blame the evil corporations of McDonald's for forcing them to eat Big Macs. They don't want to exercise. They blame the government for not providing them a trail outside their apartment to use for jogging.
But, at the same time, the pills often hamper negative physiological effects long enough to learn better ways to cope with the issue at hand.