I've been involved in discussions that highlight that incalls at personal homes are not so based on perceived safety,

But rather by schedules from outside responsibilities, economic necessity, freedom to use their home without worry of roommates/boyfriends,  
And of course, personal distrust of hotels in general, which does relate to your question.

 
Myself, personally, I feel safer in hotels, but I have canceled availability if I feel that the location is questionable.(you can PM me for details regarding little things that have led me to such a conclusion, I welcome the chance to be challenged & learn) I would only see clients I know well & have met previously at such locations, because I would have already developed a firm rapport with them.

 
I have seen clients in my own home, & immediately regreted it. They were the ones who did not feel safe in hotels, & it's definitely a string that leads to other, greater personality defects (in my experience) that I became aware of upon meeting them.  
I very quickly moved, & asked them to not contact me again.

 
Now, hosting at home versus a hotel is a perfect opportunity to pull out those ven diagrams we all learned in elementary school, but I feel that touching on that myself would leave it rather empty.

Does anyone else have any points to make